Amin Nomeir Selected Research

6- (3- cyano- 6- ethyl- 5- fluoro- 1- (pyrimidin- 2- yl)- 1H- indol- 2- yl)- N- (1,1,1- trifluoropropan- 2- yl)pyridine- 3- sulfonamide

3/2014	Structure-activity relationship (SAR) optimization of 6-(indol-2-yl)pyridine-3-sulfonamides: identification of potent, selective, and orally bioavailable small molecules targeting hepatitis C (HCV) NS4B.
7/2013	Identification of PTC725, an orally bioavailable small molecule that selectively targets the hepatitis C Virus NS4B protein.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Amin Nomeir Research Topics

Disease

4	Alzheimer Disease (Alzheimer's Disease) 12/2016 - 11/2007
3	Neoplasms (Cancer) 03/2016 - 08/2002
3	Infections 01/2016 - 07/2013
1	Hepatitis C 03/2014
1	Chronic Hepatitis C 07/2013
1	Retinoblastoma (Glioblastoma, Retinal) 08/2010

Drug/Important Bio-Agent (IBA)

3	Amyloid Precursor Protein Secretases (beta-Secretase)IBA 12/2016 - 11/2012
3	SCH 900229IBA 12/2016 - 11/2012
2	piperidineIBA 03/2016 - 11/2007
2	RNA (Ribonucleic Acid)IBA 01/2016 - 01/2016
2	6- (3- cyano- 6- ethyl- 5- fluoro- 1- (pyrimidin- 2- yl)- 1H- indol- 2- yl)- N- (1,1,1- trifluoropropan- 2- yl)pyridine- 3- sulfonamideIBA 03/2014 - 07/2013
1	pyridineIBA 03/2014
1	SulfonamidesIBA 03/2014
1	Pharmaceutical PreparationsIBA 07/2013
1	Antiviral Agents (Antivirals)IBA 07/2013
1	SulfonesIBA 02/2013
1	Presenilin-1IBA 11/2012
1	Bromodeoxyuridine (BrdU)IBA 08/2010
1	dinaciclibIBA 08/2010
1	Gamma Secretase Inhibitors and ModulatorsIBA 11/2007
1	TransferasesIBA 08/2002
1	lonafarnib (SCH 66336)IBA 08/2002

Therapy/Procedure

1	Therapeutics 07/2013
1	Oral Administration 11/2012